Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | EIF4E | P06730 | 11/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885196 | 0.89 | TSHR (0.73) | TSHREIF4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL4439669 | 0.80 | TSHR (0.59) | TSHREIF4ETDP1ALDH1A1LMNA | |
| SCHEMBL9746118 | 0.79 | ALDH1A1 (0.56) | TSHREIF4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL9746112 | 0.79 | ALDH1A1 (0.56) | TSHREIF4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL29120749 | 0.79 | MAPT (0.57) | TSHREIF4ETDP1ALDH1A1LMNA | |
| Ammonia Solution, Strong SCHEMBL28007023 | 0.79 | TSHR (0.67) | TSHRTDP1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL28002286 | 0.79 | TSHR (0.58) | TSHREIF4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL6304256 | 0.79 | TSHR (0.71) | TSHRTDP1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL28830921 | 0.79 | MYC (0.55) | TSHRALDH1A1L3MBTL1 | |
| SCHEMBL843489 | 0.78 | CYP1A2 (0.48) | TSHRTDP1ALDH1A1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070069-A1 | PROCESS FOR PREPARATION OF MEDETOMIDINE | I-TECH AB (SE) | 2011-06-16 | — | — | WO | claimed |
| WO-2011070069-A1 | PROCESS FOR PREPARATION OF MEDETOMIDINE | I-TECH AB (SE) | 2011-06-16 | — | — | WO | disclosed |