Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | DDX3X | O00571 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | DTYMK | P23919 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | EIF4E | P06730 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746118 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRDDX3XKMT2A | |
| SCHEMBL15741931 | 0.84 | TSHR (0.53) | ALDH1A1TDP1TSHRDDX3XKMT2A | |
| SCHEMBL4439669 | 0.84 | TSHR (0.59) | ALDH1A1TDP1TSHRDDX3XKMT2A | |
| SCHEMBL29120749 | 0.82 | MAPT (0.57) | ALDH1A1TDP1TSHRDDX3XKMT2A | |
| SCHEMBL29471725 | 0.79 | TSHR (0.68) | ALDH1A1TDP1TSHRKMT2AMAPT | |
| SCHEMBL8610738 | 0.79 | TSHR (0.68) | ALDH1A1TDP1TSHRKMT2AMAPT | |
| SCHEMBL3377807 | 0.79 | CASP6 (0.54) | ALDH1A1TDP1TSHRMAPTLMNA | |
| SCHEMBL2013486 | 0.79 | TSHR (0.62) | ALDH1A1TDP1TSHRDDX3XMAPT | |
| SCHEMBL30727560 | 0.79 | TSHR (0.67) | ALDH1A1TDP1TSHRKMT2AMAPT | |
| SCHEMBL29696138 | 0.79 | TSHR (0.67) | ALDH1A1TDP1TSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110869-A | Block polymerization, endcapping, coupling, chain extension | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0272285-A4 | ACYLATION AND SULFONATION OF SILYLKETENE ACETALS. | DU PONT (US) | 1990-04-10 | — | — | EP | disclosed |
| EP-0272285-A1 | ACYLATION AND SULFONATION OF SILYLKETENE ACETALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-29 | — | — | EP | disclosed |
| WO-1987007265-A1 | ACYLATION AND SULFONATION OF SILYLKETENE ACETALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-03 | — | — | WO | disclosed |