Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RBM39 | Q14498 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135307 | 0.84 | MMP13 (0.56) | ALDH1A1KMT2AMEN1MMP13 | |
| SCHEMBL20135306 | 0.84 | MMP13 (0.56) | ALDH1A1KMT2AMEN1MMP13 | |
| SCHEMBL29067991 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL31201301 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL20476798 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL20476797 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL26476141 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL28521125 | 0.81 | HRH1 (0.38) | ALDH1A1KMT2AMEN1LMNACYP3A4 | |
| SCHEMBL27951916 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL16992199 | 0.79 | F2 (0.46) | ALDH1A1KMT2AMEN1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |
| CN-107922347-A | New imide derivative and its purposes as medicine | 田边三菱制药株式会社 | 2018-04-17 | — | — | CN | disclosed |