Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26684084 | 0.81 | KDM5A (0.40) | KDM5AL3MBTL3L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL26684343 | 0.81 | KDM4E (0.42) | KDM5AKDM6BKDM4AKDM5CKDM4C | |
| SCHEMBL17404485 | 0.81 | KDM5A (0.43) | KDM5AALDH1A1KDM4E | |
| SCHEMBL20135591 | 0.81 | GPR119 (0.50) | KDM5AKDM4E | |
| SCHEMBL29303031 | 0.78 | KDM5A (0.41) | KDM5AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30344501 | 0.77 | KDM5A (0.40) | KDM5ALMNAKDM6BFAAHHDAC8 | |
| SCHEMBL28549617 | 0.77 | HRH3 (0.42) | KDM5ALMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL20809468 | 0.74 | TLR8 (0.52) | KDM5AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30177181 | 0.74 | IRAK4 (0.42) | KDM5A | |
| SCHEMBL20377779 | 0.74 | IRAK4 (0.35) | KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |