Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.30 |
| ▸ | POLRMT | O00411 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23673324 | 1.00 | TMPRSS2 (0.40) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL18605958 | 1.00 | TMPRSS2 (0.40) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL17712322 | 1.00 | TMPRSS2 (0.40) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL20550745 | 1.00 | TMPRSS2 (0.40) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL18640705 | 1.00 | TMPRSS2 (0.40) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL17760463 | 0.93 | TMPRSS2 (0.40) | TMPRSS2POLRMT | |
| SCHEMBL20135847 | 0.90 | TMPRSS2 (0.44) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL20135845 | 0.90 | TMPRSS2 (0.44) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL17712321 | 0.88 | TMPRSS2 (0.39) | TMPRSS2RIPK1 | |
| SCHEMBL23711118 | 0.87 | TMPRSS2 (0.42) | TMPRSS2RIPK1POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3366295-A1 | METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS | Gilead Sciences, Inc. (US) | 2018-08-29 | — | — | EP | disclosed |
| EP-3212174-B1 | METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2018-05-16 | — | — | EP | disclosed |