Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16708105 | 0.87 | KDM4E (0.51) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL24139263 | 0.86 | ALDH1A1 (0.50) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL24138899 | 0.86 | ALDH1A1 (0.50) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL15349723 | 0.84 | LMNA (0.51) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL20136031 | 0.78 | LMNA (0.62) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL1390620 | 0.78 | LMNA (0.43) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL20135967 | 0.78 | ALDH1A1 (0.58) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL6894785 | 0.78 | KDM4E (0.67) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL16795656 | 0.78 | CA9 (0.64) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL20136054 | 0.78 | LMNA (0.53) | LMNAKDM4EALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828269-B1 | BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF PI3K-ALPHA AND/OR BETA | COUNCIL SCIENT IND RES (IN) | 2018-05-16 | — | — | EP | disclosed |