⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013641 | 1.00 | — | — | |
| Trifluoroacetic Acid SCHEMBL2049401 | 0.88 | DPP4 (0.31) | — | |
| Trifluoroacetic Acid SCHEMBL2049405 | 0.88 | DPP4 (0.31) | — | |
| SCHEMBL2010924 | 0.75 | — | — | |
| SCHEMBL12274213 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL14844376 | 0.73 | FAP (0.30) | — | |
| Hydrochloric Acid SCHEMBL14845242 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL14845240 | 0.73 | — | — | |
| SCHEMBL2034229 | 0.72 | FAP (0.33) | — | |
| SCHEMBL2034225 | 0.72 | FAP (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11357231-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION LLC (US) | 2022-06-14 | — | — | US | disclosed |
| US-11357231-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION LLC (US) | 2022-06-14 | — | — | US | disclosed |
| US-20200383330-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2020-12-10 | — | — | US | disclosed |
| US-20200383330-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2020-12-10 | — | — | US | disclosed |
| US-10750745-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION, LLC (US) | 2020-08-25 | — | — | US | disclosed |
| US-10750745-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION, LLC (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190166842-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2019-06-06 | — | — | US | disclosed |
| US-20190166842-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2019-06-06 | — | — | US | disclosed |
| US-10206400-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-19 | — | — | US | disclosed |
| US-10206400-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-19 | — | — | US | disclosed |
| US-20140228577-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2014-08-14 | — | — | US | disclosed |
| US-8735362-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION, LLC (US) | 2014-05-27 | — | — | US | disclosed |
| US-8735362-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION, LLC (US) | 2014-05-27 | — | — | US | disclosed |
| US-8735362-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION, LLC (US) | 2014-05-27 | — | — | US | disclosed |
| EP-2507230-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | Syngenta Participations AG (CH) | 2012-10-10 | — | — | EP | disclosed |
| US-20120238517-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-20 | — | — | US | disclosed |
| US-20120238517-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-20 | — | — | US | disclosed |
| US-20120238517-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-20 | — | — | US | disclosed |
| WO-2011067272-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011067272-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |