Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034225 | 1.00 | FAP (0.33) | FAPTSHRUSP2HTTHSD17B10 | |
| SCHEMBL4760427 | 1.00 | FAP (0.33) | FAPTSHRUSP2HTTHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL2052672 | 0.87 | F2 (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL2052674 | 0.87 | F2 (0.30) | — | |
| SCHEMBL2687773 | 0.77 | — | — | |
| SCHEMBL2688336 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL2010924 | 0.76 | — | — | |
| SCHEMBL2688083 | 0.76 | RAB9A (0.38) | FAPTSHRHTTCYP3A4TDP1 | |
| SCHEMBL2687500 | 0.75 | KEAP1 (0.39) | — | |
| SCHEMBL2686766 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11357231-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION LLC (US) | 2022-06-14 | — | — | US | disclosed |
| US-11357231-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION LLC (US) | 2022-06-14 | — | — | US | disclosed |
| US-20200383330-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2020-12-10 | — | — | US | disclosed |
| US-20200383330-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2020-12-10 | — | — | US | disclosed |
| US-10750745-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION, LLC (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190166842-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2019-06-06 | — | — | US | disclosed |
| US-10206400-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-19 | — | — | US | disclosed |
| EP-2507230-B1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-17 | — | — | EP | disclosed |
| US-20170152250-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2017-06-01 | — | — | US | disclosed |
| US-9609869-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION, LLC (US) | 2017-04-04 | — | — | US | disclosed |
| US-20140228577-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2014-08-14 | — | — | US | disclosed |
| US-8735362-B2 | Insecticidal compounds based on isoxazoline derivatives | SYNGENTA CROP PROTECTION, LLC (US) | 2014-05-27 | — | — | US | disclosed |
| EP-2507230-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | Syngenta Participations AG (CH) | 2012-10-10 | — | — | EP | disclosed |
| US-20120238517-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-20 | — | — | US | disclosed |
| WO-2011067272-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228577-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | CHRM1, ACHE, CHRM2 | FAP 4845/4885TSHR 2301/4885USP2 3458/4885 |
| US-20200383330-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | CYP4X1, NPY4R, CASP3 | FAP 4816/4885TSHR 834/4885USP2 2532/4885 |
| US-20120238517-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOAZOLINE DERIVATIVES | CHRM1, ACHE, CHRM2 | FAP 4847/4885TSHR 2887/4885USP2 3695/4885 |
| US-10206400-B2 | Insecticidal compounds based on isoxazoline derivatives | CHRM1, ACHE, CHRM2 | FAP 4845/4885TSHR 2301/4885USP2 3458/4885 |
| US-11357231-B2 | Insecticidal compounds based on isoxazoline derivatives | CYP4X1, NPY4R, CASP3 | FAP 4816/4885TSHR 834/4885USP2 2532/4885 |
| US-20170152250-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | CHRM1, ACHE, CHRM2 | FAP 4845/4885TSHR 2301/4885USP2 3458/4885 |
| US-10750745-B2 | Insecticidal compounds based on isoxazoline derivatives | CHRM1, ACHE, CHRM2 | FAP 4845/4885TSHR 2301/4885USP2 3458/4885 |
| US-20190166842-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | CHRM1, ACHE, CHRM2 | FAP 4845/4885TSHR 2301/4885USP2 3458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.