Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.81 |
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20138484 | 1.00 | PTGS1 (0.81) | PTGS1MAOAMAOBMAPK1CYP3A4 | |
| SCHEMBL20138510 | 0.84 | MAOA (0.75) | PTGS1MAOAMAOBMAPK1CYP3A4 | |
| SCHEMBL31357396 | 0.84 | MAOA (0.75) | PTGS1MAOAMAOBMAPK1CYP3A4 | |
| SCHEMBL31357397 | 0.84 | MAOA (0.75) | PTGS1MAOAMAOBMAPK1CYP3A4 | |
| SCHEMBL20138512 | 0.84 | MAOA (0.75) | PTGS1MAOAMAOBMAPK1CYP3A4 | |
| SCHEMBL27836059 | 0.83 | MAOA (0.73) | PTGS1MAOAMAOBMAPK1CYP3A4 | |
| SCHEMBL31238358 | 0.82 | MAOA (1.00) | PTGS1MAOAMAOBMAPK1CYP3A4 | |
| SCHEMBL30989221 | 0.76 | PTGS1 (0.66) | PTGS1MAOAMAOBMAPK1CYP3A4 | |
| SCHEMBL4779879 | 0.73 | PTGS1 (0.57) | PTGS1MAOAMAOBMAPK1CYP3A4 | |
| SCHEMBL29682579 | 0.73 | PTGS1 (0.57) | PTGS1MAOAMAOBMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180132516-A1 | POSITIVE ALLOSTERIC MODULATORS OF SWEET TASTE | SENSORYGEN INC (US) | 2018-05-17 | — | — | US | disclosed |