Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824259 | 1.00 | PTGS1 (0.57) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL29618998 | 1.00 | PTGS1 (0.57) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL29682883 | 1.00 | PTGS1 (0.57) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL29480609 | 1.00 | PTGS1 (0.57) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL29618999 | 1.00 | PTGS1 (0.57) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL29682579 | 1.00 | PTGS1 (0.57) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL29480585 | 0.87 | MAPT (0.60) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL30554025 | 0.85 | PTGS1 (0.55) | PTGS1MAOAMAOBCYP3A4MAPT | |
| SCHEMBL21168205 | 0.80 | MAOA (0.64) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL31237248 | 0.80 | MAOA (0.64) | PTGS1MGAMMAOAMAOBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250099508-A1 | SYSTEMS, CELL LINES AND METHODS OF PRODUCING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-03-27 | — | — | US | claimed |
| EP-4460314-A2 | SYSTEMS, CELL LINES AND METHODS OF PRODUCING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-11-13 | — | — | EP | claimed |
| WO-2023130150-A2 | SYSTEMS, CELL LINES AND METHODS OF PRODUCING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-06 | — | — | WO | claimed |
| CN-119745895-A | Traditional Chinese medicine monomer composition for treating rheumatoid arthritis and application thereof | 中日友好医院(中日友好临床医学研究所) | 2025-04-04 | — | — | CN | disclosed |
| US-20250099508-A1 | SYSTEMS, CELL LINES AND METHODS OF PRODUCING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-03-27 | — | — | US | disclosed |
| EP-4460314-A2 | SYSTEMS, CELL LINES AND METHODS OF PRODUCING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-11-13 | — | — | EP | disclosed |
| CN-118576581-A | Application of pterocarpan compounds and pharmaceutical composition | 澳门科技大学 | 2024-09-03 | — | — | CN | disclosed |
| WO-2023130150-A2 | SYSTEMS, CELL LINES AND METHODS OF PRODUCING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-06 | — | — | WO | disclosed |
| CN-114533722-A | Pharmaceutical composition for treating depression | 遵义医科大学珠海校区 | 2022-05-27 | — | — | CN | disclosed |
| CN-114522172-A | Pharmaceutical composition for preventing and treating breast cancer | 遵义医科大学珠海校区 | 2022-05-24 | — | — | CN | disclosed |
| CN-104706708-A | Application of radix hedysari ethanol extract in preparation of medicine and health care products for preventing and curing liver fibrosis and effective component identification method thereof | UNIV LANZHOU | 2015-06-17 | — | — | CN | disclosed |
| US-8809627-B2 | Plant isoflavone and isoflavanone O-methyltransferase genes | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20080317880-A1 | PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES | THE SAMUEL ROBERTS NOBLE FOUNDATION | 2008-12-25 | — | — | US | disclosed |
| WO-2008022265-A2 | PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250099508-A1 | SYSTEMS, CELL LINES AND METHODS OF PRODUCING AND USING THE SAME | DCX, SLC10A2, CHAT | PTGS1 500/4885MGAM 2029/4885MAOA 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.