Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 7/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367376 | 0.85 | HRH3 (0.43) | CA2HTR1ASIGMAR1ADRA2AADRA2B | |
| SCHEMBL7321128 | 0.82 | HTR1A (0.56) | CA2HTR1AHTR1D | |
| SCHEMBL7318326 | 0.82 | HTR1A (0.56) | CA2HTR1AHTR1D | |
| SCHEMBL7317348 | 0.82 | HTR1A (0.56) | CA2HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL7312318 | 0.81 | HTR1A (0.55) | CA2HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL7315820 | 0.81 | HTR1A (0.55) | CA2HTR1AHTR1D | |
| SCHEMBL7309998 | 0.80 | HTR1A (0.57) | CA2HTR1AHTR1D | |
| SCHEMBL10366763 | 0.80 | CCR1 (0.38) | CA2 | |
| SCHEMBL4936360 | 0.78 | CA2 (0.56) | CA2HTR1ASIGMAR1ADRA2AADRA2B | |
| SCHEMBL4936349 | 0.78 | CA2 (0.56) | CA2HTR1ASIGMAR1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180132516-A1 | POSITIVE ALLOSTERIC MODULATORS OF SWEET TASTE | SENSORYGEN INC (US) | 2018-05-17 | — | — | US | disclosed |