Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484249 | 0.78 | KDM4E (0.50) | KDM4EMAP3K5ALDH1A1MAPTHPGD | |
| SCHEMBL243257 | 0.78 | MAPT (0.50) | KDM4EMAP3K5ALDH1A1MEN1KMT2A | |
| SCHEMBL9381825 | 0.77 | KDM4E (0.42) | KDM4EMAP3K5ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27665004 | 0.77 | MAPT (0.53) | KDM4EMAP3K5ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30101396 | 0.77 | MAPT (0.53) | KDM4EMAP3K5ALDH1A1MEN1KMT2A | |
| Acetic Acid SCHEMBL27461332 | 0.74 | KDM4E (0.50) | KDM4EMAP3K5ALDH1A1MEN1KMT2A | |
| Tert-Butylamine SCHEMBL27906908 | 0.73 | ALDH1A1 (0.49) | KDM4EMAP3K5ALDH1A1MEN1KMT2A | |
| SCHEMBL269086 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL28264043 | 0.72 | KDM4E (0.43) | KDM4EMAP3K5ALDH1A1MEN1KMT2A | |
| SCHEMBL27709527 | 0.72 | KDM4E (0.43) | KDM4EMAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538080-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co. Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018086139-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2018-05-17 | — | — | WO | disclosed |