Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139135 | 0.91 | KRAS (0.31) | MGLL | |
| SCHEMBL20138775 | 0.88 | KIT (0.33) | — | |
| SCHEMBL20138782 | 0.84 | P2RX7 (0.34) | — | |
| SCHEMBL20143004 | 0.82 | PIM1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL21531633 | 0.81 | PIM1 (0.32) | — | |
| SCHEMBL20154093 | 0.80 | POLB (0.34) | — | |
| SCHEMBL20139179 | 0.77 | CHRNB2 (0.35) | — | |
| SCHEMBL20138943 | 0.77 | — | — | |
| SCHEMBL20139191 | 0.76 | NPY5R (0.33) | — | |
| SCHEMBL21853825 | 0.76 | CGAS (0.34) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538523-A1 | PYRIMIDINONE DERIVATIVES AS CDC7 INHIBITORS | Cancer Research Technology Limited (GB) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018087527-A1 | PYRIMIDINONE DERIVATIVES AS CDC7 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2018-05-17 | — | — | WO | disclosed |