Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 9/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139239 | 0.89 | NR1H2 (0.50) | NR1H2NR1H3MAP4K4CHRM2CHRM1 | |
| SCHEMBL10210512 | 0.87 | FAAH (0.55) | NR1H2NR1H3MAP4K4SUV39H2GPR119 | |
| SCHEMBL20139215 | 0.87 | FAAH (0.55) | NR1H2NR1H3MAP4K4SUV39H2GPR119 | |
| SCHEMBL15378173 | 0.87 | FAAH (0.55) | NR1H2NR1H3MAP4K4SUV39H2GPR119 | |
| SCHEMBL30005266 | 0.86 | SUV39H2 (0.51) | NR1H2NR1H3MAP4K4SUV39H2GPR119 | |
| SCHEMBL16333806 | 0.85 | NR1H2 (0.48) | NR1H2NR1H3MAP4K4CHRM2CHRM1 | |
| SCHEMBL17385248 | 0.84 | MAP4K4 (0.48) | NR1H2NR1H3MAP4K4SUV39H2GPR119 | |
| SCHEMBL20139589 | 0.84 | NR1H2 (0.59) | NR1H2NR1H3MAP4K4CHRM2CHRM1 | |
| SCHEMBL19107116 | 0.83 | NR1H2 (0.46) | NR1H2NR1H3MAP4K4CHRM2CHRM1 | |
| SCHEMBL31046011 | 0.82 | ROCK2 (0.53) | NR1H2NR1H3MAP4K4SUV39H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |