Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142393 | 0.82 | MEN1 (0.56) | HSD17B10ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL27822699 | 0.79 | HSD17B10 (0.66) | KDM4EHSD17B10ALOX15ALDH1A1MEN1 | |
| SCHEMBL14562620 | 0.73 | ALDH1A1 (0.64) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL12082726 | 0.73 | KDM4E (1.00) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL20159231 | 0.72 | MTOR (0.68) | KDM4EHSD17B10ALOX15ALDH1A1MEN1 | |
| SCHEMBL4550239 | 0.72 | ALDH1A1 (0.76) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL27580597 | 0.71 | ALDH1A1 (0.82) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL34468359 | 0.71 | ALDH1A1 (0.78) | KDM4EHSD17B10ALOX15ALDH1A1MEN1 | |
| SCHEMBL3580034 | 0.70 | KDM4E (0.92) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL5909237 | 0.70 | KDM4E (0.74) | KDM4EALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |