Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139231 | 0.82 | KDM4E (0.59) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL20140557 | 0.81 | SCD5 (0.44) | MEN1KMT2AMAPTPOLBCTDSP1 | |
| SCHEMBL20139784 | 0.81 | SCD5 (0.44) | MEN1KMT2AMAPTPOLBCTDSP1 | |
| SCHEMBL20139783 | 0.81 | SCD5 (0.44) | MEN1KMT2AMAPTPOLBCTDSP1 | |
| SCHEMBL20139683 | 0.77 | KMT2A (0.51) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL20140579 | 0.75 | ALDH1A1 (0.64) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL30239278 | 0.73 | TSHR (0.63) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL28967163 | 0.73 | TSHR (0.63) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL5658689 | 0.72 | USP2 (0.78) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL20139799 | 0.72 | POLB (0.46) | ALDH1A1LMNAMAPK1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |