Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15504622 | 0.81 | SRC (0.43) | ALDH1A1MAPTLMNASRCPTGDR2 | |
| SCHEMBL20150705 | 0.80 | JAK2 (0.44) | MAPTSRCPTGDR2PSEN1PSEN2 | |
| SCHEMBL3537397 | 0.80 | PTGDR2 (0.43) | SRCPTGDR2PDE4APDE4BPDE4C | |
| SCHEMBL5004901 | 0.79 | SRC (0.41) | ALDH1A1MAPTLMNASRCPTGDR2 | |
| SCHEMBL5564252 | 0.79 | SRC (0.41) | HTR6ALDH1A1SRCPTGDR2CYP2C19 | |
| SCHEMBL30440833 | 0.79 | SRC (0.41) | HTR6ALDH1A1SRCPTGDR2CYP2C19 | |
| SCHEMBL3538021 | 0.78 | SRC (0.40) | ALDH1A1MAPTSRCPTGDR2PDE4A | |
| SCHEMBL21408924 | 0.72 | CA12 (0.38) | ALDH1A1MAPTSRCPTGDR2PDE4A | |
| SCHEMBL783826 | 0.72 | SRC (0.36) | ALDH1A1MAPTLMNASRCPTGDR2 | |
| SCHEMBL23910826 | 0.72 | ENPP3 (0.48) | ALDH1A1MAPTLMNASRCPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018088780-A1 | NOVEL PYRROLOPYRIMIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018088780-A1 | NOVEL PYRROLOPYRIMIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-05-17 | — | — | WO | disclosed |