Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139600 | 0.80 | HTR1A (0.46) | PTGDR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL15504622 | 0.76 | SRC (0.43) | NOD2NOD1PTGDR2TDP1SRC | |
| SCHEMBL3537397 | 0.75 | PTGDR2 (0.43) | NOD1PTGDR2KMT2ASRCL3MBTL1 | |
| SCHEMBL30440833 | 0.74 | SRC (0.41) | JAK2NOD2NOD1PTGDR2SRC | |
| SCHEMBL5564252 | 0.74 | SRC (0.41) | JAK2NOD2NOD1PTGDR2SRC | |
| SCHEMBL5004901 | 0.74 | SRC (0.41) | NOD2NOD1PTGDR2SRCKDM4E | |
| SCHEMBL3538021 | 0.73 | SRC (0.40) | NOD1PTGDR2KMT2ASRCKDM4E | |
| SCHEMBL7213656 | 0.72 | NOD2 (0.58) | POLBNOD2NOD1PTGDR2PSEN1 | |
| SCHEMBL23326637 | 0.69 | PTGDR2 (0.49) | NOD2NOD1PTGDR2KMT2AKDM4E | |
| SCHEMBL29190430 | 0.69 | BACE1 (0.36) | PTGDR2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018088780-A1 | NOVEL PYRROLOPYRIMIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-05-17 | — | — | WO | disclosed |