Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 11/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 11/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139753 | 1.00 | SUV39H2 (0.43) | SUV39H2MAP4K4GPR119FAAHNR1H2 | |
| SCHEMBL20141793 | 1.00 | SUV39H2 (0.43) | SUV39H2MAP4K4GPR119FAAHNR1H2 | |
| SCHEMBL20157182 | 0.93 | SUV39H2 (0.43) | SUV39H2MAP4K4GPR119FAAHNR1H2 | |
| SCHEMBL20142084 | 0.81 | MAP4K4 (0.41) | SUV39H2MAP4K4GPR119NR1H2NR1H3 | |
| SCHEMBL29182836 | 0.81 | SUV39H2 (0.39) | SUV39H2MAP4K4GPR119NR1H2NR1H3 | |
| SCHEMBL29182837 | 0.81 | SUV39H2 (0.39) | SUV39H2MAP4K4GPR119NR1H2NR1H3 | |
| SCHEMBL20159029 | 0.80 | SUV39H2 (0.49) | SUV39H2MAP4K4GPR119FAAHNR1H2 | |
| SCHEMBL30124281 | 0.77 | GPR119 (0.35) | SUV39H2MAP4K4GPR119HDAC1SETD7 | |
| SCHEMBL29182882 | 0.77 | GPR119 (0.35) | SUV39H2MAP4K4GPR119HDAC1SETD7 | |
| SCHEMBL31160729 | 0.75 | SUV39H2 (0.36) | SUV39H2MAP4K4GPR119FAAHNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |