Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.37 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141789 | 0.86 | GPR119 (0.41) | MAP4K4GPR119HDAC1SUV39H2SETD7 | |
| SCHEMBL20157182 | 0.81 | SUV39H2 (0.43) | MAP4K4GPR119HDAC1SUV39H2NR1H2 | |
| SCHEMBL20139753 | 0.81 | SUV39H2 (0.43) | MAP4K4GPR119HDAC1SUV39H2SETD7 | |
| SCHEMBL20141793 | 0.81 | SUV39H2 (0.43) | MAP4K4GPR119HDAC1SUV39H2SETD7 | |
| SCHEMBL20139752 | 0.81 | SUV39H2 (0.43) | MAP4K4GPR119HDAC1SUV39H2SETD7 | |
| SCHEMBL29182837 | 0.79 | SUV39H2 (0.39) | MAP4K4GPR119HDAC1SUV39H2SETD7 | |
| SCHEMBL29182836 | 0.79 | SUV39H2 (0.39) | MAP4K4GPR119HDAC1SUV39H2SETD7 | |
| SCHEMBL20159137 | 0.76 | BRD4 (0.34) | — | |
| SCHEMBL30124281 | 0.75 | GPR119 (0.35) | MAP4K4GPR119HDAC1SUV39H2SETD7 | |
| SCHEMBL29182882 | 0.75 | GPR119 (0.35) | MAP4K4GPR119HDAC1SUV39H2SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |