Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.40 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140861 | 0.91 | GRM1 (0.51) | GRM1HSD11B1KDM4EALDH1A1TDP1 | |
| SCHEMBL20140709 | 0.87 | GRM1 (0.50) | GRM1HSD11B1MTORRPTORMLST8 | |
| SCHEMBL20142060 | 0.87 | GRM1 (0.50) | GRM1HSD11B1MTORRPTORMLST8 | |
| SCHEMBL20141549 | 0.84 | GRM1 (0.49) | GRM1HSD11B1KDM4EALDH1A1TDP1 | |
| SCHEMBL20141184 | 0.83 | GRM1 (0.47) | GRM1HSD11B1KDM4EALDH1A1TDP1 | |
| SCHEMBL20140644 | 0.78 | GRM1 (0.42) | GRM1HSD11B1KDM4EALDH1A1TDP1 | |
| SCHEMBL20141860 | 0.78 | GRM1 (0.47) | GRM1HSD11B1MTORRPTORMLST8 | |
| SCHEMBL20141266 | 0.78 | GRM1 (0.51) | GRM1HSD11B1KDM4EALDH1A1TDP1 | |
| SCHEMBL20142471 | 0.76 | DRD2 (0.42) | GRM1HSD11B1MTORRPTORMLST8 | |
| SCHEMBL20142472 | 0.76 | DRD2 (0.42) | GRM1HSD11B1MTORRPTORMLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |