Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21561028 | 0.78 | JAK2 (0.37) | JAK2TYK2DRD4 | |
| SCHEMBL7400751 | 0.78 | SCN9A (0.43) | DRD2HTR1AHTR7DRD4GRM5 | |
| SCHEMBL3436003 | 0.78 | KEAP1 (0.49) | — | |
| SCHEMBL3436310 | 0.78 | ADRB1 (0.59) | HTR1AHTR7 | |
| SCHEMBL5373038 | 0.78 | MEN1 (0.49) | — | |
| SCHEMBL233169 | 0.76 | ADRB1 (0.58) | DRD2HTR1AHTR7DRD3 | |
| SCHEMBL2560845 | 0.75 | PIM1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL29882725 | 0.75 | ADRB1 (0.56) | DRD2HTR1AHTR7DRD3 | |
| Hydrochloric Acid SCHEMBL20139829 | 0.75 | ADRB1 (0.56) | DRD2HTR1AHTR7DRD3 | |
| SCHEMBL19066690 | 0.74 | KDM4E (0.49) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |