Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | STS | P08842 | 10/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16501440 | 0.81 | KMT2A (0.56) | KMT2ALMNAEPHX2STSPTPN2 | |
| SCHEMBL13261261 | 0.80 | STS (0.54) | KMT2ASTSPTPN2PTPN1PTPN6 | |
| SCHEMBL3711728 | 0.80 | STS (0.57) | KMT2ASTSPTPN2PTPN1PTPN6 | |
| SCHEMBL18183705 | 0.79 | PTPN2 (0.48) | KMT2ASTSPTPN2PTPN1PTPN6 | |
| SCHEMBL21633596 | 0.78 | STS (0.51) | KMT2AEPHX2STSPTPN2PTPN1 | |
| SCHEMBL2963673 | 0.77 | STS (0.48) | KMT2AEPHX2STSPTPN2PTPN1 | |
| SCHEMBL4235957 | 0.77 | MGLL (0.56) | KMT2ASTSPTPN2PTPN1PTPN6 | |
| SCHEMBL25452815 | 0.76 | STS (0.51) | KMT2ASTSPTPN2PTPN1PTPN6 | |
| SCHEMBL17495365 | 0.76 | USP30 (0.50) | KMT2ASTSPTPN2PTPN1PTPN6 | |
| SCHEMBL13261291 | 0.76 | GPR119 (0.52) | KMT2AEPHX2STSPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |