Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 18/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141184 | 0.86 | GRM1 (0.47) | GRM1HSD11B1 | |
| SCHEMBL20141860 | 0.83 | GRM1 (0.47) | GRM1HSD11B1CYP2D6GSK3B | |
| SCHEMBL20140128 | 0.83 | GRM1 (0.45) | GRM1HSD11B1CYP2D6GSK3B | |
| SCHEMBL20139954 | 0.83 | POLB (0.45) | HSD11B1 | |
| SCHEMBL20139834 | 0.82 | GRM1 (0.41) | GRM1HSD11B1CYP2D6GSK3B | |
| SCHEMBL20142060 | 0.82 | GRM1 (0.50) | GRM1HSD11B1CYP2D6 | |
| SCHEMBL20140709 | 0.82 | GRM1 (0.50) | GRM1HSD11B1CYP2D6 | |
| SCHEMBL20141109 | 0.79 | MTOR (0.40) | GRM1HSD11B1CYP2D6 | |
| SCHEMBL20141108 | 0.79 | MTOR (0.40) | GRM1HSD11B1CYP2D6 | |
| SCHEMBL20140644 | 0.75 | GRM1 (0.42) | GRM1HSD11B1CYP2D6GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |