Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.41 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.41 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141391 | 0.87 | MEN1 (0.35) | LMNAGRM5MEN1KMT2AEED | |
| SCHEMBL16991986 | 0.86 | ABCB1 (0.43) | GRM5EEDRBBP4SUZ12EZH2 | |
| SCHEMBL20140796 | 0.84 | EED (0.43) | LMNAGRM5MEN1KMT2AEED | |
| SCHEMBL1602307 | 0.82 | OGA (0.46) | LMNAGRM5MEN1KMT2ANR1H2 | |
| SCHEMBL6392515 | 0.81 | GRM5 (0.45) | GRM5MEN1KMT2ANR1H2ESR2 | |
| SCHEMBL6615891 | 0.79 | GRM5 (0.45) | GRM5EEDRBBP4SUZ12EZH2 | |
| SCHEMBL20333548 | 0.79 | KMT2A (0.46) | GRM5MEN1KMT2ANR1H2HDAC1 | |
| SCHEMBL20304927 | 0.79 | KMT2A (0.46) | GRM5MEN1KMT2ANR1H2HDAC1 | |
| SCHEMBL20304926 | 0.79 | KMT2A (0.46) | GRM5MEN1KMT2ANR1H2HDAC1 | |
| SCHEMBL4959967 | 0.78 | ESR2 (0.46) | GRM5MEN1KMT2ANR1H2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |