Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 4/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140065 | 0.87 | LMNA (0.43) | MEN1KMT2ALMNAGRM5EED | |
| SCHEMBL20157093 | 0.76 | GRM5 (0.38) | LMNAWNT3AGRM5GRM1EED | |
| SCHEMBL16991986 | 0.76 | ABCB1 (0.43) | GRM5EEDRBBP4SUZ12EZH2 | |
| SCHEMBL29826188 | 0.73 | GRM5 (0.44) | WNT3AGRM5GRM1CCNT1CDK9 | |
| SCHEMBL20140796 | 0.73 | EED (0.43) | MEN1KMT2ALMNAGRM5EED | |
| SCHEMBL25487258 | 0.72 | ALDH1A1 (0.53) | MEN1KMT2ALMNACYP2C19SMN1; SMN2 | |
| SCHEMBL29826797 | 0.72 | HTT (0.50) | KMT2ALMNAGRM5GRM1NAMPT | |
| SCHEMBL1602307 | 0.71 | OGA (0.46) | MEN1KMT2ALMNAGRM5NR1H2 | |
| SCHEMBL18321407 | 0.71 | PDK4 (0.44) | GRM5GRM1NAMPTPDK4NR1H2 | |
| SCHEMBL20140685 | 0.70 | EED (0.48) | LMNAEEDRBBP4SUZ12EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |