Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.43 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.43 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140065 | 0.84 | LMNA (0.43) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL31738746 | 0.84 | EED (0.41) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL6615891 | 0.81 | GRM5 (0.45) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL15057509 | 0.79 | GRM5 (0.43) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL14720690 | 0.77 | KMT2A (0.45) | GRM5NR1H2LMNAKMT2AMEN1 | |
| SCHEMBL1602307 | 0.77 | OGA (0.46) | GRM5NR1H2LMNAKMT2AMEN1 | |
| SCHEMBL16991986 | 0.76 | ABCB1 (0.43) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL25346497 | 0.76 | ESR2 (0.57) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL29784626 | 0.76 | ESR2 (0.57) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL23044100 | 0.76 | ESR2 (0.56) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |