Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959176 | 0.88 | NPSR1 (0.44) | NPSR1HMGB1CXCL12GABRPGABRD | |
| SCHEMBL13199185 | 0.86 | NPSR1 (0.41) | NPSR1HMGB1CXCL12GABRPGABRD | |
| SCHEMBL20140904 | 0.79 | PDGFRB (0.46) | NPSR1KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL69934 | 0.78 | KDM4E (0.50) | HMGB1CXCL12GABRPGABRDGABRA1 | |
| SCHEMBL15957874 | 0.78 | NPSR1 (0.45) | NPSR1HMGB1CXCL12GABRPGABRD | |
| SCHEMBL20141358 | 0.76 | KDM4E (0.41) | HMGB1CXCL12GABRPGABRDGABRA1 | |
| SCHEMBL29350418 | 0.75 | KDM4E (0.50) | HMGB1CXCL12GABRPGABRDGABRA1 | |
| SCHEMBL238021 | 0.75 | KDM4E (0.50) | HMGB1CXCL12GABRPGABRDGABRA1 | |
| SCHEMBL30932083 | 0.75 | GABRP (0.48) | HMGB1CXCL12GABRPGABRDGABRA1 | |
| SCHEMBL12931051 | 0.75 | NPSR1 (0.47) | NPSR1HMGB1CXCL12GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |