SCHEMBL69934

SCHEMBL69934

Cc1cc(C)c(C(=O)O)cc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.50
ALDH1A1 P00352 4/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
NOTUM Q6P988 1/20 0.50
GABRP O00591 1/20 0.50
GABRD O14764 1/20 0.50
GABRA1 P14867 1/20 0.50
GABRB1 P18505 1/20 0.50
GABRG2 P18507 1/20 0.50
GABRB3 P28472 1/20 0.50
GABRA5 P31644 1/20 0.50
GABRA3 P34903 1/20 0.50
GABRA2 P47869 1/20 0.50
GABRB2 P47870 1/20 0.50
GABRA4 P48169 1/20 0.50
GABRE P78334 1/20 0.50
GABRA6 Q16445 1/20 0.50
GABRG1 Q8N1C3 1/20 0.50
GABRG3 Q99928 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30932083 0.97 GABRP (0.48) KDM4EALDH1A1HPGDHSD17B10NOTUM
SCHEMBL2400964 0.92 KDM4E (0.50) KDM4EALDH1A1HPGDHSD17B10NOTUM
SCHEMBL238021 0.92 KDM4E (0.50) KDM4EALDH1A1HPGDHSD17B10NOTUM
SCHEMBL29350418 0.92 KDM4E (0.50) KDM4EALDH1A1HPGDHSD17B10NOTUM
SCHEMBL70135 0.91 KDM4E (0.54) KDM4EALDH1A1HPGDHSD17B10NOTUM
Hydrochloric Acid SCHEMBL4352648 0.88 KDM4E (0.52) KDM4EALDH1A1HPGDHSD17B10NOTUM
Ethylene SCHEMBL6034661 0.86 KDM4E (0.50) KDM4EALDH1A1HPGDHSD17B10NOTUM
SCHEMBL13199099 0.85 KDM4E (0.48) KDM4EALDH1A1HPGDHSD17B10NOTUM
SCHEMBL27289129 0.85 CSNK2A1 (0.54) KDM4EALDH1A1HPGDHSD17B10GABRP
SCHEMBL15544006 0.84 KDM4E (0.43) KDM4EALDH1A1HPGDHSD17B10NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894793-B Swelling-resistant adhesive ionic gel and preparation method and application thereof 中国海洋大学 2024-05-28 CN claimed
CN-114106320-B Wholly aromatic high-temperature resistant nylon and preparation method and application thereof 惠生(中国)投资有限公司 2023-09-19 CN claimed
CN-114106320-A Wholly aromatic high-temperature-resistant nylon and preparation method and application thereof 惠生(中国)投资有限公司 2022-03-01 CN claimed
CN-108690200-B Metal organic structure and method for producing same 丰田自动车株式会社 2021-07-16 CN claimed
US-10702851-B2 Metal-organic framework and method of manufacturing the same TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2020-07-07 US claimed
EP-3381924-B1 METAL-ORGANIC FRAMEWORK AND METHOD OF MANUFACTURING THE SAME TOYOTA MOTOR CO LTD (JP) 2019-10-16 EP claimed
CN-108690200-A Metal organic structure body and its manufacturing method 丰田自动车株式会社 2018-10-23 CN claimed
US-20180280929-A1 METAL-ORGANIC FRAMEWORK AND METHOD OF MANUFACTURING THE SAME TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2018-10-04 US claimed
EP-3381924-A1 METAL-ORGANIC FRAMEWORK AND METHOD OF MANUFACTURING THE SAME Toyota Jidosha Kabushiki Kaisha (JP) 2018-10-03 EP claimed
CN-104583197-B New bicyclicpyridine derivatives 霍夫曼-拉罗奇有限公司 2017-05-17 CN claimed
US-20240294025-A1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LIMITED (JP) 2024-09-05 US disclosed
CN-115894793-B Swelling-resistant adhesive ionic gel and preparation method and application thereof 中国海洋大学 2024-05-28 CN disclosed
CN-117615915-A Thermosensitive recording material 三菱制纸株式会社 2024-02-27 CN disclosed
CN-114106320-B Wholly aromatic high-temperature resistant nylon and preparation method and application thereof 惠生(中国)投资有限公司 2023-09-19 CN disclosed
CN-115894793-A Swelling-resistant adhesive ionic gel and preparation method and application thereof 中国海洋大学 2023-04-04 CN disclosed
CN-1251586-A Noval pyrimidine derivatives and process and preparing thereof YUHAN CORP (KR) 2000-04-26 CN disclosed
CN-1155281-A Noval pyrimidine derivatives and prepn. processes thereof YUHAN CORP (KR) 1997-07-23 CN disclosed
US-4016206-A PROCESS FOR PREPARING PYROMELLITIC ACID GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-04-05 US disclosed
US-3991012-A AGAINST ULTRAVIOLET DETERIORATION OF POLYMERS CIBA-GEIGY CORPORATION (US) 1976-11-09 US disclosed
US-3969405-A ACID ACTIVATOR OSTROWICK PIERRE M J G DE RADZ 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180280929-A1 METAL-ORGANIC FRAMEWORK AND METHOD OF MANUFACTURING THE SAME TRIM4, TRIM24, PICALM KDM4E 1786/4885ALDH1A1 2308/4885HPGD 4453/4885
US-10702851-B2 Metal-organic framework and method of manufacturing the same TRIM4, TRIM24, PICALM KDM4E 1786/4885ALDH1A1 2308/4885HPGD 4453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.