Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 2/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 4/20 | 0.33 |
| ▸ | CCND1 | P24385 | 4/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14981577 | 0.84 | F2RL1 (0.35) | F2RL1RHEBCDK4CCND1HTR1D | |
| SCHEMBL18876106 | 0.78 | F2RL1 (0.42) | F2RL1RHEBCDK4CCND1CCNE2 | |
| SCHEMBL10211053 | 0.76 | KDM4E (0.33) | — | |
| SCHEMBL24981842 | 0.73 | F2RL1 (0.40) | F2RL1RHEBCDK4CCND1CCNE2 | |
| SCHEMBL6030234 | 0.73 | PRMT1 (0.36) | CDK4CCND1CCNE1CDK2 | |
| SCHEMBL2123551 | 0.72 | IMPDH2 (0.36) | — | |
| SCHEMBL19584831 | 0.72 | ALDH1A1 (0.39) | F2RL1RHEBCDK4CCND1CCNE2 | |
| SCHEMBL31589251 | 0.72 | F2RL1 (0.39) | F2RL1RHEBCDK4CCND1CCNE2 | |
| SCHEMBL22320207 | 0.71 | — | — | |
| SCHEMBL31364619 | 0.71 | GAA (0.34) | RHEBCDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |