Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | TERT | O14746 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25398562 | 1.00 | PPARG (0.53) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL20140197 | 1.00 | PPARG (0.53) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL28665578 | 1.00 | PPARG (0.53) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL29214408 | 1.00 | PPARG (0.53) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL25397513 | 0.98 | PPARG (0.50) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL11511124 | 0.94 | PPARG (0.58) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL182419 | 0.94 | PPARG (0.58) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL10344108 | 0.94 | PPARG (0.58) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL28945766 | 0.94 | PPARG (0.58) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL29448232 | 0.94 | PPARG (0.58) | PPARGPPARATERTMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240101594-A1 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. | 2024-03-28 | — | — | US | disclosed |
| US-11760775-B2 | Steroids and protein-conjugates thereof | REGENERON PHARMACEUTICALS, INC. | 2023-09-19 | — | — | US | disclosed |
| US-20230218726-A1 | TREATMENT OF VIRAL CONJUNCTIVITIS | OKOGEN, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230085022-A1 | COMBINATION THERAPIES OF PREDNISONE AND URICASE MOLECULES AND USES THEREOF | HORIZON THERAPEUTICS USA, INC. | 2023-03-16 | — | — | US | disclosed |
| EP-4138882-A1 | TREATMENT OF VIRAL CONJUNCTIVITIS | Okogen, Inc. (US) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021216909-A1 | TREATMENT OF VIRAL CONJUNCTIVITIS | OKOGEN, INC. (US) | 2021-10-28 | — | — | WO | disclosed |
| US-20210040144-A1 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. | 2021-02-11 | — | — | US | disclosed |
| US-10711032-B2 | Steroids and protein-conjugates thereof | REGENERON PHARMACEUTICALS, INC. (US) | 2020-07-14 | — | — | US | disclosed |
| US-20200199538-A1 | DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS | AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR (SG) | 2020-06-25 | — | — | US | disclosed |
| EP-3538539-A2 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | Regeneron Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| EP-3538135-A1 | COMBINATION THERAPIES OF PREDNISONE AND URICASE MOLECULES AND USES THEREOF | Horizon Pharma Rheumatology LLC (US) | 2019-09-18 | — | — | EP | disclosed |
| US-20180258400-A1 | DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) (SG) | 2018-09-13 | — | — | US | disclosed |
| WO-2018089373-A9 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |
| US-20180155389-A1 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. | 2018-06-07 | — | — | US | disclosed |
| WO-2018089808-A1 | COMBINATION THERAPIES OF PREDNISONE AND URICASE MOLECULES AND USES THEREOF | HORIZON PHARMA RHEUMATOLOGY LLC (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089373-A2 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101594-A1 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | SERPINA6, NR3C1, NR3C2 | PPARG 1234/4885PPARA 2537/4885TERT 4690/4885 |
| US-20180155389-A1 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | SERPINA6, NR3C1, NR3C2 | PPARG 1177/4885PPARA 2415/4885TERT 4700/4885 |
| US-10711032-B2 | Steroids and protein-conjugates thereof | SERPINA6, NR3C1, NR3C2 | PPARG 1177/4885PPARA 2415/4885TERT 4700/4885 |
| US-20210040144-A1 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | SERPINA6, NR3C1, NR3C2 | PPARG 1234/4885PPARA 2537/4885TERT 4690/4885 |
| US-11760775-B2 | Steroids and protein-conjugates thereof | SERPINA6, NR3C1, NR3C2 | PPARG 1234/4885PPARA 2537/4885TERT 4690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.