Sugi Predict

Sugi Predict / Compounds / SCHEMBL20140197

SCHEMBL20140197

SCHEMBL20140197

CCC=CC(=O)C=CCCCCCCCCCC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 3/20 0.53
▸ PPARA Q07869 3/20 0.53
▸ TERT O14746 3/20 0.52
▸ MAPT P10636 2/20 0.52
▸ BLM P54132 2/20 0.52
▸ HSD17B10 Q99714 2/20 0.52
▸ FABP4 P15090 2/20 0.52
▸ GMNN O75496 1/20 0.52
▸ USP2 O75604 1/20 0.52
▸ LMNA P02545 1/20 0.52
▸ CYP1A2 P05177 1/20 0.52
▸ POLB P06746 1/20 0.52
▸ CYP2C9 P11712 1/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ APEX1 P27695 1/20 0.52
▸ CYP2C19 P33261 1/20 0.52
▸ RECQL P46063 1/20 0.52
▸ NPSR1 Q6W5P4 1/20 0.52
▸ DUSP3 P51452 1/20 0.52
▸ MMP2 P08253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25398562 1.00 PPARG (0.53) PPARGPPARATERTMAPTBLM
SCHEMBL28665578 1.00 PPARG (0.53) PPARGPPARATERTMAPTBLM
SCHEMBL20140196 1.00 PPARG (0.53) PPARGPPARATERTMAPTBLM
SCHEMBL29214408 1.00 PPARG (0.53) PPARGPPARATERTMAPTBLM
SCHEMBL25397513 0.98 PPARG (0.50) PPARGPPARATERTMAPTBLM
SCHEMBL11511124 0.94 PPARG (0.58) PPARGPPARATERTMAPTBLM
SCHEMBL182419 0.94 PPARG (0.58) PPARGPPARATERTMAPTBLM
SCHEMBL10344108 0.94 PPARG (0.58) PPARGPPARATERTMAPTBLM
SCHEMBL28945766 0.94 PPARG (0.58) PPARGPPARATERTMAPTBLM
SCHEMBL29448232 0.94 PPARG (0.58) PPARGPPARATERTMAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110582564-A derivation of liver organoids from human pluripotent stem cells 新加坡科技研究局 2019-12-17 — — CN claimed
US-20260008997-A1 CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION GENENTECH, INC. (US) 2026-01-08 — — US disclosed
US-12377159-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-08-05 — — US disclosed
US-20240101594-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2024-03-28 — — US disclosed
US-11760775-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. 2023-09-19 — — US disclosed
CN-116637177-A Combination therapy of prednisone and uricase molecules and uses thereof 好利恩治疗美国公司 2023-08-25 — — CN disclosed
US-20230218726-A1 TREATMENT OF VIRAL CONJUNCTIVITIS OKOGEN, INC. 2023-07-13 — — US disclosed
CN-115996715-A Treatment of viral conjunctivitis 奥可金公司 2023-04-21 — — CN disclosed
US-20230085022-A1 COMBINATION THERAPIES OF PREDNISONE AND URICASE MOLECULES AND USES THEREOF HORIZON THERAPEUTICS USA, INC. 2023-03-16 — — US disclosed
EP-4138882-A1 TREATMENT OF VIRAL CONJUNCTIVITIS Okogen, Inc. (US) 2023-03-01 — — EP disclosed
US-10711032-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2020-07-14 — — US disclosed
US-20200199538-A1 DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR (SG) 2020-06-25 — — US disclosed
CN-110582564-A derivation of liver organoids from human pluripotent stem cells 新加坡科技研究局 2019-12-17 — — CN disclosed
EP-3538135-A1 COMBINATION THERAPIES OF PREDNISONE AND URICASE MOLECULES AND USES THEREOF Horizon Pharma Rheumatology LLC (US) 2019-09-18 — — EP disclosed
EP-3538539-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2019-09-18 — — EP disclosed
US-20180258400-A1 DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) (SG) 2018-09-13 — — US disclosed
WO-2018089373-A9 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2018-07-12 — — WO disclosed
US-20180155389-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2018-06-07 — — US disclosed
WO-2018089808-A1 COMBINATION THERAPIES OF PREDNISONE AND URICASE MOLECULES AND USES THEREOF HORIZON PHARMA RHEUMATOLOGY LLC (US) 2018-05-17 — — WO disclosed
WO-2018089373-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2018-05-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240101594-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 PPARG 1234/4885PPARA 2537/4885TERT 4690/4885
US-20180155389-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 PPARG 1177/4885PPARA 2415/4885TERT 4700/4885
US-20260008997-A1 CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION CD99, BHMT, PROC PPARG 4834/4885PPARA 4746/4885TERT 1811/4885
US-10711032-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 PPARG 1177/4885PPARA 2415/4885TERT 4700/4885
US-12377159-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 PPARG 1234/4885PPARA 2537/4885TERT 4690/4885
US-11760775-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 PPARG 1234/4885PPARA 2537/4885TERT 4690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.