Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 6/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.46 |
| ▸ | PARP3 | Q9Y6F1 | 3/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140663 | 0.84 | SMN1; SMN2 (0.51) | KDM4EALDH1A1PARP1CFTR | |
| SCHEMBL20139883 | 0.80 | MTOR (0.54) | KDM4EALDH1A1TDP1PARP1HDAC2 | |
| SCHEMBL20156981 | 0.76 | MTOR (0.58) | KDM4EALDH1A1TDP1PARP1MALT1 | |
| SCHEMBL20140694 | 0.75 | MTOR (0.50) | ALDH1A1PARP1CFTR | |
| SCHEMBL5901321 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1TDP1RECQLHDAC2 | |
| SCHEMBL3576933 | 0.74 | SLC6A7 (0.65) | KDM4EALDH1A1TDP1PARP1RECQL | |
| SCHEMBL14566007 | 0.74 | KDM4E (0.62) | KDM4EALDH1A1TDP1RECQLHDAC2 | |
| SCHEMBL13862949 | 0.74 | KDM4E (0.65) | KDM4EALDH1A1TDP1PARP1RECQL | |
| SCHEMBL29678394 | 0.74 | KDM4E (0.65) | KDM4EALDH1A1TDP1PARP1RECQL | |
| SCHEMBL6235112 | 0.73 | KDM4E (0.61) | KDM4EALDH1A1TDP1PARP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |