Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.49 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.49 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140608 | 0.88 | MTOR (0.56) | MTORRPTORMLST8DRD2HTR2A | |
| SCHEMBL20140023 | 0.85 | MTOR (0.61) | MTORRPTORMLST8DRD2HTR2A | |
| SCHEMBL20139966 | 0.85 | MTOR (0.61) | MTORRPTORMLST8DRD2HTR2A | |
| SCHEMBL20156921 | 0.84 | MTOR (0.51) | MTORRPTORMLST8AVPR1ADRD2 | |
| SCHEMBL20157035 | 0.82 | NPC1 (0.46) | MTORRPTORMLST8MEN1KMT2A | |
| SCHEMBL20141890 | 0.82 | MTOR (0.51) | MTORRPTORMLST8DRD2HTR2A | |
| SCHEMBL20140558 | 0.82 | MTOR (0.51) | MTORRPTORMLST8DRD2HTR2A | |
| SCHEMBL20139946 | 0.81 | MTOR (0.48) | MTORRPTORMLST8MEN1KMT2A | |
| SCHEMBL20140751 | 0.81 | MTOR (0.60) | MTORRPTORMLST8DRD2HTR2A | |
| SCHEMBL20156794 | 0.80 | MTOR (0.54) | MTORRPTORMLST8DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |