Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139638 | 0.85 | MLYCD (0.37) | HPGDMEN1KMT2AMLYCDTDP1 | |
| SCHEMBL30845490 | 0.85 | MLYCD (0.37) | HPGDMEN1KMT2AMLYCDTDP1 | |
| SCHEMBL16018694 | 0.82 | MEN1 (0.35) | HPGDMEN1KMT2AMLYCDTDP1 | |
| SCHEMBL13265347 | 0.79 | MLYCD (0.40) | MLYCDCLK1DYRK1ADYRK1BALDH1A1 | |
| SCHEMBL156978 | 0.78 | ALDH1A1 (0.46) | HPGDMEN1KMT2ATDP1CLK1 | |
| SCHEMBL1349358 | 0.78 | MEN1 (0.45) | MEN1KMT2AMLYCDTDP1CLK1 | |
| SCHEMBL2272338 | 0.78 | MLYCD (0.45) | HPGDMEN1KMT2AMLYCDTDP1 | |
| SCHEMBL15216403 | 0.78 | HPGD (0.59) | HPGDMEN1KMT2AMLYCDTDP1 | |
| SCHEMBL29696047 | 0.78 | ALDH1A1 (0.46) | HPGDMEN1KMT2ATDP1CLK1 | |
| SCHEMBL616327 | 0.77 | MEN1 (0.35) | HPGDMEN1KMT2AMLYCDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |