Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18239280 | 0.84 | KDM4E (0.42) | ERN1KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL17262516 | 0.84 | SLC22A6 (0.38) | TTRKDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL20140332 | 0.82 | ERN1 (0.44) | ERN1KDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL12488767 | 0.82 | GRIA1 (0.41) | ERN1KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL30281117 | 0.82 | GRIA1 (0.41) | ERN1KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL12593947 | 0.80 | KDM4E (0.45) | KDM4EASPHKDM8ALDH1A1NOTUM | |
| SCHEMBL691736 | 0.80 | GRIA1 (0.48) | ERN1KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL24891886 | 0.79 | ALDH1A1 (0.42) | ERN1KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL365017 | 0.78 | KDM4E (0.44) | KDM4EASPHKDM8ALDH1A1NOTUM | |
| SCHEMBL27523055 | 0.78 | KDM4E (0.44) | TTRKDM4EASPHKDM8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |