Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | DRD5 | P21918 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27762499 | 0.73 | KDM1A (0.43) | GBA1SLC6A4MEN1CYP2D6KMT2A | |
| SCHEMBL5274832 | 0.71 | KDM4E (0.44) | NOTUMMEN1KMT2AGABRPGABRD | |
| SCHEMBL20140659 | 0.70 | PLAT (0.40) | MEN1CYP2D6KMT2A | |
| SCHEMBL20139848 | 0.70 | KDM4E (0.42) | NOTUMMEN1KMT2AGABRPGABRD | |
| SCHEMBL20141358 | 0.69 | KDM4E (0.41) | NOTUMMEN1KMT2AGABRPGABRD | |
| SCHEMBL5190879 | 0.67 | IRAK4 (0.36) | — | |
| SCHEMBL23230317 | 0.67 | SLC6A4 (0.44) | MAOAGBA1SLC6A4 | |
| SCHEMBL27411185 | 0.67 | KDM4E (0.54) | NOTUMMEN1KMT2AGABRPGABRD | |
| SCHEMBL28086811 | 0.66 | GBA1 (0.51) | MAOAGBA1SLC6A4 | |
| SCHEMBL28794378 | 0.65 | MAOA (0.41) | MAOAGBA1SLC6A4PPARGTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |