Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.35 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL20140974 | 0.85 | CHRM4 (0.42) | CHRM1CHRM5CHRM3CHRM4CHRM2 | |
| Trifluoroacetic Acid SCHEMBL20140975 | 0.85 | CHRM4 (0.42) | CHRM1CHRM5CHRM3CHRM4CHRM2 | |
| SCHEMBL20156829 | 0.83 | MTOR (0.43) | CHRM1CHRM5CHRM3CHRM4CHRM2 | |
| Trifluoroacetic Acid SCHEMBL20141710 | 0.81 | MTOR (0.43) | CHRM1CHRM5CHRM3CHRM4CHRM2 | |
| SCHEMBL20156947 | 0.80 | MTOR (0.45) | CHRM1CHRM5CHRM4CHRM2MTOR | |
| SCHEMBL20156830 | 0.72 | MTOR (0.51) | MTORRPTORMLST8 | |
| SCHEMBL20142001 | 0.72 | MTOR (0.47) | CHRM4MTORRPTORMLST8 | |
| SCHEMBL20142004 | 0.72 | MTOR (0.47) | CHRM4MTORRPTORMLST8 | |
| SCHEMBL20141016 | 0.71 | MTOR (0.53) | CHRM4CHRM2MTORRPTORMLST8 | |
| SCHEMBL20141592 | 0.69 | MTOR (0.43) | CHRM4CHRM2MTORRPTORMLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |