Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MPI | P34949 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17408855 | 0.77 | BCHE (0.37) | KCNJ1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30786784 | 0.77 | LMNA (0.34) | KCNJ1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL24771606 | 0.77 | LMNA (0.34) | KCNJ1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7106759 | 0.75 | TDP1 (0.52) | TDP1CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL7511807 | 0.74 | TDP1 (0.39) | TDP1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL31337139 | 0.70 | ALDH1A1 (0.32) | HTR2BALDH1A1 | |
| SCHEMBL22342564 | 0.70 | ALDH1A1 (0.32) | HTR2BALDH1A1 | |
| SCHEMBL14036990 | 0.69 | TDP1 (0.46) | TDP1CYP1A2CYP3A4 | |
| SCHEMBL31613762 | 0.68 | KCNJ1 (0.37) | KCNJ1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1912446 | 0.68 | KCNJ1 (0.37) | KCNJ1KDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |