Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404952 | 1.00 | GPR119 (0.53) | GPR119MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL17866332 | 0.94 | MEN1 (0.54) | GPR119MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL1513265 | 0.93 | GPR119 (0.57) | GPR119MAPTNAMPTRETKDM4E | |
| SCHEMBL3436375 | 0.85 | HSD11B1 (0.54) | GPR119MAPTHPGDSPDE4BUSP30 | |
| SCHEMBL38652150 | 0.84 | GPR119 (0.45) | GPR119MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL25378846 | 0.82 | GPR119 (0.56) | GPR119PDE4BRET | |
| SCHEMBL21352382 | 0.82 | GPR119 (0.50) | GPR119MAPTHPGDSPDE4BUSP30 | |
| SCHEMBL2078377 | 0.82 | GPR119 (0.50) | GPR119MAPTHPGDSPDE4BUSP30 | |
| SCHEMBL28334298 | 0.82 | GPR119 (0.50) | GPR119MAPTHPGDSPDE4BUSP30 | |
| SCHEMBL31321190 | 0.82 | GPR119 (0.52) | GPR119MAPTNAMPTRETKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |