Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.44 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139953 | 0.84 | CHRM2 (0.46) | MTORRPTORMLST8ALDH1A1MAPT | |
| SCHEMBL20139868 | 0.84 | MTOR (0.52) | MTORRPTORMLST8ALDH1A1HTT | |
| SCHEMBL20140694 | 0.82 | MTOR (0.50) | MTORRPTORMLST8ALDH1A1HTT | |
| SCHEMBL20157344 | 0.77 | MTOR (0.50) | MTORRPTORMLST8SLC6A9SLC6A5 | |
| SCHEMBL20156938 | 0.76 | MTOR (0.51) | MTORRPTORMLST8ALDH1A1HTT | |
| SCHEMBL20140684 | 0.76 | MTOR (0.51) | MTORRPTORMLST8ALDH1A1HTT | |
| SCHEMBL20140350 | 0.74 | MTOR (0.54) | MTORRPTORMLST8SLC6A9SLC6A5 | |
| SCHEMBL20140663 | 0.74 | SMN1; SMN2 (0.51) | MTORRPTORMLST8ALDH1A1HTT | |
| SCHEMBL20140583 | 0.74 | CHRM2 (0.43) | MTORRPTORMLST8ALDH1A1MAPT | |
| SCHEMBL20140314 | 0.74 | CHRM2 (0.43) | MTORRPTORMLST8ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |