Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 4/20 | 0.32 |
| ▸ | NOS3 | P29474 | 3/20 | 0.32 |
| ▸ | NOS1 | P29475 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141151 | 0.89 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3CYP2D6NOS2 | |
| SCHEMBL20140846 | 0.88 | SLC6A2 (0.37) | SLC6A2SLC6A4HCRTR1HCRTR2SLC6A3 | |
| SCHEMBL20141147 | 0.83 | SLC6A2 (0.38) | SLC6A2SLC6A4HCRTR1HCRTR2SLC6A3 | |
| SCHEMBL20141029 | 0.83 | SLC6A2 (0.38) | SLC6A2SLC6A4HCRTR1HCRTR2SLC6A3 | |
| SCHEMBL20141030 | 0.81 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3NOS2NOS3 | |
| SCHEMBL20140933 | 0.81 | SLC6A2 (0.36) | SLC6A2SLC6A4HCRTR1HCRTR2SLC6A3 | |
| SCHEMBL20141036 | 0.77 | KCNH2 (0.37) | SLC6A2SLC6A4HCRTR1HCRTR2SLC6A3 | |
| SCHEMBL20141038 | 0.77 | KCNH2 (0.37) | SLC6A2SLC6A4HCRTR1HCRTR2SLC6A3 | |
| SCHEMBL20141245 | 0.76 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3NOS2NOS3 | |
| SCHEMBL20141342 | 0.75 | SLC6A2 (0.36) | SLC6A2SLC6A4NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |