Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.43 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.43 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 13/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141225 | 0.90 | MTOR (0.41) | MTORRPTORMLST8 | |
| SCHEMBL20140898 | 0.81 | SLC6A4 (0.41) | SLC6A2SLC6A4 | |
| SCHEMBL20141054 | 0.77 | MTOR (0.48) | MTORRPTORMLST8 | |
| SCHEMBL20141029 | 0.77 | SLC6A2 (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL20141353 | 0.77 | SLC6A2 (0.39) | SLC6A2SLC6A4KDM1A | |
| SCHEMBL20141091 | 0.76 | MTOR (0.45) | MTORRPTORMLST8FASN | |
| SCHEMBL20141216 | 0.76 | SLC6A2 (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL20141214 | 0.76 | SLC6A2 (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL20141181 | 0.75 | SLC6A4 (0.41) | SLC6A2SLC6A4 | |
| SCHEMBL20141263 | 0.75 | MTOR (0.46) | MTORRPTORMLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |