Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 8/20 | 0.42 |
| ▸ | HTR2B | P41595 | 7/20 | 0.42 |
| ▸ | HTR2A | P28223 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9396845 | 1.00 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL20140710 | 0.98 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL27529782 | 0.90 | SLC6A4 (0.53) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL21360355 | 0.87 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL4238187 | 0.87 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL20140984 | 0.87 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL8248575 | 0.87 | HTR7 (0.52) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL5394683 | 0.86 | NOTUM (0.43) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL27613840 | 0.86 | HTR3E (0.45) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL8595770 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |