Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 7/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | SMO | Q99835 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129733 | 0.86 | GPR119 (0.50) | GRM1TRPV1HSD11B1RBP4 | |
| SCHEMBL4262115 | 0.81 | TRPV1 (0.64) | TRPV1HSD11B1 | |
| SCHEMBL4258832 | 0.81 | TRPV1 (0.55) | GRM1TRPV1SMOHSD11B1AVPR1A | |
| SCHEMBL4258836 | 0.81 | TRPV1 (0.55) | GRM1TRPV1SMOHSD11B1AVPR1A | |
| SCHEMBL20140927 | 0.79 | CA1 (0.47) | TRPV1HSD11B1 | |
| SCHEMBL4266990 | 0.78 | TRPV1 (0.69) | GRM1TRPV1HSD11B1RBP4 | |
| SCHEMBL20141349 | 0.77 | SMO (0.45) | GRM1SMOSLC6A7 | |
| SCHEMBL20129734 | 0.76 | PRKCQ (0.45) | TRPV1HSD11B1 | |
| SCHEMBL16236002 | 0.76 | GRM1 (0.64) | GRM1SMOSLC6A7 | |
| SCHEMBL20133726 | 0.74 | CHIA (0.48) | TRPV1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |