Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141741 | 0.88 | MTOR (0.42) | EEDALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL20141150 | 0.87 | CA12 (0.40) | EEDALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL20141228 | 0.84 | MTOR (0.45) | EEDCA12CA1CA2CA9 | |
| SCHEMBL20140814 | 0.84 | MTOR (0.45) | EEDALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL20141317 | 0.82 | MTOR (0.46) | MAPTHTTCA12CA1CA2 | |
| SCHEMBL20141403 | 0.82 | MTOR (0.43) | MAPTHTTLMNATSHR | |
| SCHEMBL20141024 | 0.81 | MTOR (0.46) | EEDALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL20141263 | 0.80 | MTOR (0.46) | MAPTHTTCA12CA1CA2 | |
| SCHEMBL20140851 | 0.79 | MTOR (0.44) | ALDH1A1SMN1; SMN2MAPTHTTCA12 | |
| SCHEMBL20141169 | 0.78 | MTOR (0.45) | ALDH1A1SMN1; SMN2MAPTHTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |