Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.50 |
| ▸ | CKS1B | P61024 | 2/20 | 0.47 |
| ▸ | SKP1 | P63208 | 2/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.47 |
| ▸ | DTYMK | P23919 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10317314 | 0.85 | POLB (0.58) | POLBGPR119CKS1BSKP1SKP2 | |
| SCHEMBL20129609 | 0.84 | POLB (0.46) | POLBGPR119CKS1BSKP1SKP2 | |
| SCHEMBL20141848 | 0.83 | EED (0.40) | ALDH1A1LMNAMAPT | |
| SCHEMBL22391780 | 0.82 | POLB (0.58) | POLBGPR119CKS1BSKP1SKP2 | |
| SCHEMBL30592004 | 0.81 | POLB (0.57) | POLBGPR119CKS1BSKP1SKP2 | |
| SCHEMBL21401570 | 0.81 | POLB (0.57) | POLBGPR119CKS1BSKP1SKP2 | |
| SCHEMBL14206364 | 0.81 | POLB (0.57) | POLBGPR119CKS1BSKP1SKP2 | |
| SCHEMBL123592 | 0.81 | POLB (0.71) | POLBGPR119CKS1BSKP1SKP2 | |
| SCHEMBL20919401 | 0.80 | POLB (0.56) | POLBGPR119CKS1BSKP1SKP2 | |
| SCHEMBL30292496 | 0.80 | POLB (0.56) | POLBGPR119CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |