Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141718 | 0.81 | CKS1B (0.45) | CKS1BSKP1SKP2DRD2IDO1 | |
| SCHEMBL20139539 | 0.80 | ALDH1A1 (0.39) | DRD2BRD4 | |
| SCHEMBL31357676 | 0.80 | BCHE (0.47) | DRD2BRD4 | |
| SCHEMBL18765017 | 0.77 | POLB (0.46) | DRD2BRD4 | |
| SCHEMBL17619511 | 0.76 | ALDH1A1 (0.56) | CKS1BSKP1SKP2DRD2IDO1 | |
| SCHEMBL6417674 | 0.75 | MAPT (0.39) | DRD2BRD4IDO1 | |
| Hydrochloric Acid SCHEMBL14736483 | 0.74 | PDE10A (0.47) | CKS1BSKP1SKP2DRD2BRD4 | |
| SCHEMBL18942729 | 0.74 | AKT1 (0.49) | CKS1BSKP1SKP2DRD2IDO1 | |
| SCHEMBL1313637 | 0.74 | BRD9 (0.46) | CKS1BSKP1SKP2DRD2IDO1 | |
| SCHEMBL28092204 | 0.74 | ALDH1A1 (0.40) | DRD2IDO1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |