Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 3/20 | 0.45 |
| ▸ | SKP1 | P63208 | 3/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16297436 | 0.82 | ALDH1A1 (0.39) | IDO1DRD2MEN1KMT2ASIGMAR1 | |
| SCHEMBL16297447 | 0.82 | SYK (0.41) | CKS1BSKP1SKP2IDO1DRD2 | |
| SCHEMBL20141217 | 0.81 | CKS1B (0.42) | CKS1BSKP1SKP2IDO1DRD2 | |
| SCHEMBL31357676 | 0.78 | BCHE (0.47) | DRD2MEN1KMT2ABCHE | |
| SCHEMBL16297438 | 0.77 | ALDH1A1 (0.35) | DRD2MEN1KMT2ASIGMAR1 | |
| SCHEMBL16297444 | 0.76 | SIGMAR1 (0.42) | IDO1DRD2MEN1POLBKMT2A | |
| SCHEMBL24930987 | 0.75 | CKS1B (0.47) | CKS1BSKP1SKP2IDO1DRD2 | |
| SCHEMBL30835688 | 0.73 | S1PR1 (0.42) | CKS1BSKP1SKP2IDO1DRD2 | |
| SCHEMBL1313637 | 0.73 | BRD9 (0.46) | CKS1BSKP1SKP2IDO1DRD2 | |
| SCHEMBL17619511 | 0.73 | ALDH1A1 (0.56) | CKS1BSKP1SKP2IDO1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |