Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1139401 | 0.82 | LOXL2 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4209249 | 0.79 | CA2 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6492578 | 0.77 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12708553 | 0.76 | KMT2A (0.41) | CA12CA9LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL14207286 | 0.76 | KMT2A (0.39) | CA12CA9LMNAL3MBTL1HPGD | |
| SCHEMBL1743952 | 0.75 | CYP4F2 (0.38) | KDM4EPOLBCYP4F2CYP4A11MAPT | |
| SCHEMBL2650418 | 0.75 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL455338 | 0.73 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8719755 | 0.73 | LOXL2 (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1408485 | 0.72 | CA12 (0.56) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11878046-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | OHIO STATE INNOVATION FOUNDATION (US) | 2024-01-23 | — | — | US | disclosed |
| US-11351222-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | OHIO STATE INNOVATION FOUNDATION (US) | 2022-06-07 | — | — | US | disclosed |
| US-20220160819-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-05-26 | — | — | US | disclosed |
| US-20190282654-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2019-09-19 | — | — | US | disclosed |
| EP-3538125-A2 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | Ohio State Innovation Foundation (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089648-A2 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190282654-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | IKBKE, IKBKB, SHARPIN | CA12 4345/4885CA1 2710/4885CA2 4152/4885 |
| US-11878046-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | IKBKE, IKBKB, SHARPIN | CA12 4345/4885CA1 2710/4885CA2 4152/4885 |
| US-20220160819-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | IKBKE, IKBKB, SHARPIN | CA12 4345/4885CA1 2710/4885CA2 4152/4885 |
| US-11351222-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | IKBKE, IKBKB, SHARPIN | CA12 4345/4885CA1 2710/4885CA2 4152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.